Download Files:

TC-I2000

SKU T8449-5 mg Category Small Compound Brand: TargetMol

Price range: 48 CAD through 435 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

10 mg 100 mg 200 mg 25 mg 5 mg 50 mg

Clear

Products Details

Product Description

– TC-I2000 is an TRPM8 channel blocker. Inhibits icilin-induced TRPM8 channel activation in rTRPM8-expressing CHO cells with IC50 of 53 nM.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T8449

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C23H18F4N2O

References

– Tamayo N A , Bo Y , Gore V , et al. Fused Piperidines as a Novel Class of Potent and Orally Available Transient Receptor Potential Melastatin Type 8 (TRPM8) Antagonists[J]. Journal of Medicinal Chemistry, 2012, 55(4):1593-1611.

CAS Number

– 1159996-20-9

Molecular Weight

– C23H18F4N2O

Compound Purity

– 0.9887

SMILES

– C(NC1=CC=C(F)C=C1)(=O)N2C(C=3C(CC2)=CC=CC3)C4=CC=C(C(F)(F)F)C=C4

Pathway

– Membrane transporter/Ion channel

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.