Tau-aggregation and neuroinflammation-IN-1

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Tau-aggregation and neuroinflammation-IN-1

SKU T62899-10 mg Category Small Compound Brand: TargetMol

Price range: 61 CAD through 282 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

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Products Details

Product Description

– Tau-aggregation and neuroinflammation-IN-1 is a potent inhibitor of tau protein aggregates, showing significant inhibitory activity against AcPHF6 and full-length tau protein aggregates. It has anti-inflammatory activity, reduces NO release, exhibits low cytotoxicity against LSP-stimulated BV2 cells, and reverses okadaic acid-induced memory impairment in rats.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T62899

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C25H20N2O7

References

– Shi CJ, et al. Usnic acid derivatives as tau-aggregation and neuroinflammation inhibitors. Eur J Med Chem. 2020 Feb 1;187:111961.

CAS Number

– 2175953-98-5

Molecular Weight

– C25H20N2O7

Compound Purity

– 1

SMILES

– C[C@@]12C=3C(OC1=CC4=C(C2=O)C(C)=NN4C5=CC=C(C(O)=O)C=C5)=C(C(C)=O)C(O)=C(C)C3O

Pathway

– Immunology/Inflammation|||Cytoskeletal Signaling

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.