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Tarloxotinib bromide

SKU T13088-1 mL * 10 mM (in DMSO) Category Small Compound Brand: TargetMol

Price range: 229 CAD through 2,208 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

1 mg 1 mL * 10 mM (in DMSO)10 mg 100 mg 25 mg 5 mg 50 mg

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Products Details

Product Description

– Tarloxotinib bromide (TH-4000) is an irreversible inhibitor of EGFR/HER2.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T13088

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C24H24Br2ClN9O3

References

– Adam V Patterson, et al. Abstract 5358: The hypoxia-activated EGFR-TKI TH-4000 overcomes erlotinib-resistance in preclinical NSCLC models at plasma levels achieved in a Phase 1 clinical trial. AACR 106th Annual Meeting 2015; April 18-22, 2015; Philadelphia, PA.

CAS Number

– 1636180-98-7

Molecular Weight

– C24H24Br2ClN9O3

Compound Purity

– 0.9715

SMILES

– [Br-].Cn1cnc(c1C[N+](C)(C)CC=CC(=O)Nc1cc2c(Nc3ccc(Cl)c(Br)c3)ncnc2cn1)[N+]([O-])=O

Target

– Others

Pathway

– Angiogenesis|||Tyrosine Kinase/Adaptors|||JAK/STAT signaling

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.