TAK-441
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TAK-441

SKU T21325-1 mg Category Brand:

Price range: 160 CAD through 1,589 CAD

Products Details

Product Description

– TAK-441 is an orally active inhibitor of Hedgehog signaling(IC50 = 4.4 nM) with potent antitumor activity. TAK-441 suppresses transcription factor Gli1 mRNA expression and tumor growth.

Web ID

– T21325

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C28H31F3N4O6

References

– Goldman J, et al. Phase 1 Dose-Escalation Trial of the Oral Investigational Hedgehog Signaling Pathway Inhibitor TAK-441 in Patients with Advanced Solid Tumors. Clin Cancer Res. 2014 Dec 12.

CAS Number

– 1186231-83-3

Molecular Weight

– C28H31F3N4O6

Compound Purity

– 0.9879

SMILES

– O(CC(F)(F)F)C=1C2=C(N(C)C1C(NC3CCN(C(CO)=O)CC3)=O)C=C(CC)N(CC(=O)C4=CC=CC=C4)C2=O

Pathway

– Stem Cells|||GPCR/G Protein

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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