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T16Ainh-A01

SKU T13059-1 mg Category Small Compound Brand: TargetMol

Price range: 48 CAD through 1,282 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

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Products Details

Product Description

– T16Ainh-A01 is a potent inhibitor of TMEM16A Chloride channel, inhibiting TMEM16A-mediated chloride currents (IC50 of 1 μM),and functions as a calcium-activated chloride channel (CaCC).

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T13059

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C19H20N4O3S2

Citations

– 1. Shi S, Ma B, Sun F, et al. Zafirlukast inhibits the growth of lung adenocarcinoma via inhibiting TMEM16A channel activity. Journal of Biological Chemistry. 2022, 298(3).

References

– Fedigan S, et al. Effects of new-generation TMEM16A inhibitors on calcium-activated chloride currents in rabbit urethral interstitial cells of Cajal. Pflugers Arch. 2017 Nov;469(11):1443-1455.

CAS Number

– 552309-42-9

Molecular Weight

– C19H20N4O3S2

Compound Purity

– 0.9815

SMILES

– CCc1c(C)[nH]c(SCC(=O)Nc2nc(cs2)-c2ccc(OC)cc2)nc1=O

Target

– Others

Pathway

– Membrane transporter/Ion channel

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.