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STAT3-IN-20

SKU T79662-25 mg Category Small Compound Brand: TargetMol

Price range: 2,672 CAD through 4,480 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

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Products Details

Product Description

– STAT3-IN-20 (Compound 40), with an IC50 of 0.65 μM, is a selective inhibitor targeting the SH2 domain of STAT3, thereby impeding its phosphorylation, nuclear translocation, and subsequent gene transcription. The compound demonstrates antiproliferative effects on DU145 and MDA-MB-231 cancer cell lines, which have overactivated STAT3, with IC50 values of 2.97 μM and 3.26 μM, respectively. Moreover, STAT3-IN-20 induces cell cycle arrest and apoptosis [1].

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T79662

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C30H27F4N7S

CAS Number

– 2768427-54-7

Molecular Weight

– C30H27F4N7S

SMILES

– N(C=1C=C2C(N(C(=N2)C3=CC=C(F)C=C3)C4CC4)=CC1N5CCN(C)CC5)C=6SC(=NN6)C7=CC=C(C(F)(F)F)C=C7

Pathway

– JAK/STAT signaling|||Stem Cells

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.