SLW131

Name: SLW131 | R7 Agonist | Buy Online | Immunomart
Brand: TargetMol
SKU: T205065-10 mg

SKU T205065-10 mg Category Small Compound Brand: TargetMol

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Products Details

Product Description

– SLW131 (Compound 10) is a CCR7 antagonist with strong affinity, showing a Ki of 9.85 nM. It inhibits CCL19-induced Go protein activation with an IC50 of 29.4 μM and β-arrestin2 recruitment with an IC50 of 6.0 μM. SLW131 also suppresses CCL19-induced morphological changes in primary BMDC cells and CCR7-mediated migration of mouse CD4+ T cells.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T205065

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C21H27N5O5S

CAS Number

– 681511-84-2

Molecular Weight

– C21H27N5O5S

SMILES

– N([C@H]([C@@](C)(C)C)C=1OC(C)=CC1)C=2C(NC3=C(O)C(C(N(C)C)=O)=CC=C3)=NS(=O)(=O)N2

Pathway

– Autophagy|||GPCR/G Protein|||Immunology/Inflammation

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.