Download Files:

SL327

SKU T2708-1 mL * 10 mM (in DMSO) Category Small Compound Brand: TargetMol

Price range: 50 CAD through 261 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

1 mL * 10 mM (in DMSO)10 mg 100 mg 25 mg 5 mg 50 mg

Clear

Products Details

Product Description

– SL327 is a selective inhibitor for MEK1/2 with IC50 of 0.18 μM/0.22 μM; able to transport through the blood-brain barrier.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T2708

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C16H12F3N3S

Citations

– 1. Zhu H, Liu X, Wang X, et al.Gβγ subunit inhibitor decreases DOM-induced head twitch response via the PLCβ/IP3/Ca2+/ERK and cAMP signaling pathways.European Journal of Pharmacology.2023: 176038.

References

– Scherle PA, wt al. J Biol Chem. 2000, 275(47), 37086-37092.

CAS Number

– 305350-87-2

Molecular Weight

– C16H12F3N3S

Compound Purity

– 0.98

SMILES

– NC(Sc1ccc(N)cc1)=C(C#N)c1ccccc1C(F)(F)F

Pathway

– Cell Cycle/Checkpoint|||MAPK|||DNA Damage/DNA Repair

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.