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Products Details
Product Description
– SIRT5 inhibitor 4 (compound 11) is a potent, selective SIRT5 inhibitor with IC50 values of 26.4 and >400μM for SIRT5 and other SIRT subtype, respectively[1].
Web ID
– HY-150727
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C18H15N3O4S
References
– [1]Han LY, et, al. Identification of 2-hydroxybenzoic acid derivatives as selective SIRT5 inhibitors. Eur.J.Med.Chem.2022 Jul 22, 114623
CAS Number
– 708992-34-1
Molecular Weight
– 369.39
SMILES
– CC(NC(C=C1)=CC=C1C2=CSC(NC3=CC=C(C(O)=O)C(O)=C3)=N2)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Sirtuin
Isoform
– SIRT1;SIRT2;SIRT3;SIRT5;SIRT6;SIRT7
Pathway
– Cell Cycle/DNA Damage;Epigenetics
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
