Siglec-5 Protein (Primary Amine Labeling), Human, Recombinant (hFc), Biotinylated

SKU TMPK-00720-100 μg Category Recombinant-Protein Brand: TargetMol

Price range: 1,302 CAD through 5,200 CAD

Size

100 μg 500 μg

Clear

Products Details

Product Description

– Group B Streptococcus (GBS) causes invasive infections in human newborns. the GBS β-protein attenuates innate immune responses by binding to sialic acid-binding immunoglobulin-like lectin 5 (Siglec-5), an inhibitory receptor on phagocytes.the polymorphism could influence the risk of prematurity among human fetuses of mothers colonized with GBS. This first functionally proven example of a paired receptor system in the Siglec family has multiple implications for regulation of host immunity.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– TMPK-00720

Storage Temperature

– -20℃

Shipping

– Blue Ice

References

– Ali SR, et al. Siglec-5 and Siglec-14 are polymorphic paired receptors that modulate neutrophil and amnion signaling responses to group B Streptococcus. J Exp Med. 2014 Jun 2;211(6):1231-42. doi: 10.1084/jem.20131853. Epub 2014 May 5. PMID: 24799499; PMCID: PMC4042635.

Molecular Weight

Product type

– Recombinant-Protein

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.