SFNGGP-NH2

Name: SFNGGP-NH2 | Research Reagent — Buy Online | Immunomart
Brand: TargetMol
SKU: T80234-5 mg

SKU T80234-5 mg Category Peptide Brand: TargetMol

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Products Details

Product Description

– SFNGGP-NH2 is a biologically active peptide that interacts with Protease-Activated Receptor 3 (PAR-3), a high-affinity thrombin receptor. Human cutaneous mast cells express PAR-3 mRNA, implicating a role in itch mechanotransduction, with both histamine-dependent and independent pathways reported. While PAR-3 alone does not induce itch, it may potentiate itch when co-expressed with PAR-4, enhancing thrombin’s action. This suggests that PAR-3’s primary function is not as a signal transmitter across the membrane, but rather as a cofactor necessary for PAR-4 activation.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T80234

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C25H36N8O8

CAS Number

– 261521-21-5

Molecular Weight

– C25H36N8O8

SMILES

– C(CNC(CNC([C@@H](NC([C@H](CC1=CC=CC=C1)NC([C@H](CO)N)=O)=O)CC(N)=O)=O)=O)(=O)N2[C@H](C(N)=O)CCC2

Product type

– Peptide

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.