Download Files:

SB 216763

SKU T3077-1 mL * 10 mM (in DMSO) Category Small Compound Brand: TargetMol

Price range: 53 CAD through 1,354 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

2 mg 1 mL * 10 mM (in DMSO)10 mg 100 mg 25 mg 5 mg 50 mg 500 mg

Clear

Products Details

Product Description

– SB 216763 (SB216763) is an effective and specific GSK-3α/β inhibitor (IC50: 34.3 nM).

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T3077

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C19H12Cl2N2O2

Citations

– 1. Ruan B, Liu W, Chen P, et al. NVP-BEZ235 inhibits thyroid cancer growth by p53- dependent/independent p21 upregulation. International Journal of Biological Sciences. 2020, 16(4): 682 2. Wu L, Lin W, Liao Q, et al. Calcium Channel Blocker Nifedipine Suppresses Colorectal Cancer Progression and Immune Escape by Preventing NFAT2 Nuclear Translocation. Cell Reports. 2020, 33(4): 108327

References

– Coghlan MP, et al. Chem Biol, 2000, 7(10), 793-803.

CAS Number

– 280744-09-4

Molecular Weight

– C19H12Cl2N2O2

Compound Purity

– 0.9961

SMILES

– O=C1C(C=2C=3C(N(C)C2)=CC=CC3)=C(C(=O)N1)C4=C(Cl)C=C(Cl)C=C4

Pathway

– Autophagy|||PI3K/Akt/mTOR signaling|||Stem Cells

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.