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SAR131675

SKU T6012-1 mL * 10 mM (in DMSO) Category Small Compound Brand: TargetMol

Price range: 48 CAD through 1,045 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

1 mg 1 mL * 10 mM (in DMSO)10 mg 100 mg 200 mg 25 mg 5 mg 50 mg

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Products Details

Product Description

– SAR131675 is a potent and selective VEGFR3 inhibitor with an IC50 of 23 nM.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T6012

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C18H22N4O4

Citations

– 1. Wang C, Xu J, Cheng X, et al.Anti-lymphangiogenesis for boosting drug accumulation in tumors.Signal Transduction and Targeted Therapy.2024, 9(1): 89.

References

– Alam A, et al. SAR131675, a potent and selective VEGFR-3-TK inhibitor with antilymphangiogenic, antitumoral, and antimetastatic activities. Mol Cancer Ther. 2012 Aug;11(8):1637-49.

CAS Number

– 1433953-83-3

Molecular Weight

– C18H22N4O4

Compound Purity

– 0.9974

SMILES

– C(C)N1C=2C(C(=O)C(C(NC)=O)=C1N)=CC=C(C#C[C@@](COC)(C)O)N2

Pathway

– Tyrosine Kinase/Adaptors|||Angiogenesis

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.