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Products Details
Product Description
– (S)-HH2853 (compound 200), a PYRIDINO five membered aromatic ring compound, is a potent EZH1/2 dual inhibitor with an IC50 of <100 nM for EZH2_Y641F. (S)-HH2853 has the potential to be used in the research of anti-tumor or autoimmune diseases[1].
Web ID
– HY-144881
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C31H36F3N7O3
References
– [1]Xuxing Chen, et al. PYRIDINO five membered aromatic ring compounds, preparation method and application thereof. WO2018045971A1.
CAS Number
– 2202678-05-3
Molecular Weight
– 611.66
SMILES
– C[C@H](N1CCN(CC1)CC(F)(F)F)C2=C(C)C(C(NCC3=C(C=C(NC3=O)C)OC)=O)=CC4=C(C5=CC=C(N=N5)C)C=CN24
Clinical Information
– No Development Reported
Research Area
– Cancer; Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– Histone Methyltransferase
Isoform
– EZH1;EZH2
Pathway
– Epigenetics
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
