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(S)-GFB-12811
$480
Only 1000 item(s) left in stock.
Products Details
Product Description
– (S)-GFB-12811 (compound 596) is a potent and selective CDK5 inhibitor, with an IC50 value less than 10 nM. (S)-GFB-12811 can be used in the research of cell cycle progression, neuronal development, tumorigenesis[1].
Web ID
– HY-144117A
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C22H23F4N5O
References
– [1]Malojcic Goran, et al. Substituted 1,6-naphthyridines as inhibitors of CDK5 and their preparation. Patent WO2022011274.
CAS Number
– 2757672-69-6
Molecular Weight
– 449.44
Compound Purity
– 97.12
SMILES
– C[C@@](C1=NC2=C(C=NC(NC3=C(F)C=NC(C(F)(F)F)=C3)=C2)C=C1)(C4CCN(CC4)C)O
Clinical Information
– No Development Reported
Research Area
– Cancer; Neurological Disease
Solubility
– 10 mM in DMSO
Target
– CDK
Isoform
– CDK2;CDK5
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
