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(S)-AMPA
$340 – $550
Products Details
Product Description
– (S)-AMPA (L-AMPA), an active S-enantiomer of AMPA, is a potent and selective AMPA receptor agonist[1][2].
Web ID
– HY-100815A
Storage Temperature
– -20°C, 3 years (Powder)
Shipping
– Blue Ice
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C7H10N2O4
References
– [1]J A Larm, et al. (S)-5-fluorowillardiine-mediated neurotoxicity in cultured murine cortical neurones occurs via AMPA and kainate receptors. Eur J Pharmacol. 1996 Oct 24;314(1-2):249-54.|[2]B Ebert, et al. Molecular pharmacology of the AMPA agonist, (S)-2-amino-3-(3-hydroxy-5-phenyl-4-isoxazolyl)propionic acid [(S)-APPA] and the AMPA antagonist, (R)-APPA. Neurochem Int. 1994 Jun;24(6):507-15.|[3]J W Brooks, et al. (S)-AMPA inhibits electrically evoked calcitonin gene-related peptide (CGRP) release from the rat dorsal horn: reversal by cannabinoid receptor antagonist SR141716A. Neurosci Lett. 2004 Nov 30;372(1-2):85-8.|[4]J A Larm, et al. Apoptosis induced via AMPA-selective glutamate receptors in cultured murine cortical neurons. J Neurochem. 1997 Aug;69(2):617-22.
CAS Number
– 83643-88-3
Molecular Weight
– 186.17
Compound Purity
– 99.0
SMILES
– O=C1C(C[C@H](N)C(O)=O)=C(C)ON1
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– H2O : 18.7 mg/mL (ultrasonic;warming)
Target
– iGluR
Isoform
– AMPA Receptor
Pathway
– Membrane Transporter/Ion Channel;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
