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(S)-3,5-DHPG
$330 – $363
Products Details
Product Description
– (S)-3,5-DHPG is a weak, but selective group I metabotropic glutamate receptors (mGluRs) agonist with Ki values of 0.9 µM and 3.9 µM for mGluR1a and mGluR5a, respectively[1]. (S)-3,5-DHPG exhibits anxiolytic activity in rats subjected to hypoxia[2].
Web ID
– HY-12598
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C8H9NO4
References
– [1]V Mutel, et al. Characterization of [(3)H]Quisqualate Binding to Recombinant Rat Metabotropic Glutamate 1a and 5a Receptors and to Rat and Human Brain Sections. J Neurochem. 2000 Dec;75(6):2590-601.|[2]Agnieszka Nadlewska, et al. Effect of (S)-3,5-DHPG on Learning, Exploratory Activity and Anxiety in Rats With Experimental Hypoxia. Pol J Pharmacol. Jan-Feb 2002;54(1):11-8.
CAS Number
– 162870-29-3
Molecular Weight
– 183.16
Compound Purity
– 99.0
SMILES
– O=C(O)[C@@H](N)C1=CC(O)=CC(O)=C1
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– DMSO : 100 mg/mL (ultrasonic)|H2O : 25 mg/mL (ultrasonic)
Target
– mGluR
Isoform
– mGluR1;mGluR5
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
