S-(1-Hydroxy-2-methylpropan-2-yl) methanesulfonothioate

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S-(1-Hydroxy-2-methylpropan-2-yl) methanesulfonothioate

SKU T18653-2 mg Category PROTAC Brand: TargetMol

Price range: 123 CAD through 202 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

2 mg 5 mg

Clear

Products Details

Product Description

– S-(1-Hydroxy-2-methylpropan-2-yl) methanesulfonothioate, an ADC linker, is a glutathione-cleavable compound used for attaching monoclonal antibodies (mAb) in antibody-drug conjugates (ADCs), specifically referring to the Alkyl-Chain composition of the linker portion of these molecules [1].

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T18653

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C5H12O3S2

References

– Pillow TH, et al. Antibody Conjugation of a Chimeric BET Degrader Enables in vivo Activity. ChemMedChem. 2019 Oct 31.

CAS Number

– 2127875-65-2

Molecular Weight

– C5H12O3S2

SMILES

– CC(C)(CO)SS(C)(=O)=O

Target

– Raf

Pathway

– Antibody-drug Conjugate/ADC Related

Product type

– PROTAC

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.