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(RS)-MCPG
$38 – $780
Products Details
Product Description
– (RS)-MCPG (alpha-MCPG) is a competitive and selective group I/group II metabotropic glutamate receptor (mGluR) antagonist. (RS)-MCPG blocks theta-burst stimulation (TBS)-induced shifts in both juvenile and neonatal rat hippocampal neurons[1][2].
Web ID
– HY-100371
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C10H11NO4
References
– [1]Yang B et al. Regulation of GABA Equilibrium Potential by mGluRs in Rat Hippocampal CA1 Neurons. PLoS One, 2015 Sep 21, 10(9):e0138215.|[2]Fiona Yeuk-Lun Choi, et al. The effects of (RS)-MCPG on amphetamine-induced sensitization in neonatal rats.
CAS Number
– 146669-29-6
Molecular Weight
– 209.20
Compound Purity
– 99.05
SMILES
– CC(C(O)=O)(N)C1=CC=C(C(O)=O)C=C1
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 1M NaOH : 100 mg/mL (ultrasonic;adjust pH to 10 with NaOH)|DMSO : 6 mg/mL (ultrasonic;warming)|H2O : < 0.1 mg/mL (ultrasonic;heat to 80°C)
Target
– mGluR
Isoform
– mGluR
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
