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Roxadustat

SKU T2515-1 mL * 10 mM (in DMSO) Category Small Compound Brand: TargetMol

Price range: 48 CAD through 459 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

1 mL * 10 mM (in DMSO)10 mg 100 mg 25 mg 5 mg 50 mg 500 mg

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Products Details

Product Description

– Roxadustat (FG-4592) is an orally bioavailable, hypoxia-inducible factor prolyl hydroxylase inhibitor (HIF-PHI), with potential anti-anemic activity.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T2515

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C19H16N2O5

Citations

– 1. Wang J, Aniwan A, Liu H, et al.O-GlcNAcylation regulates HIF-1α and induces mesothelial-mesenchymal transition and fibrosis of human peritoneal mesothelial cells.Heliyon.2023 2. Wang J, Lv X, Lin Y, et al.Genistein inhibits HIF-1α and attenuates high glucose-induced peritoneal mesothelial-mesenchymal transition and fibrosis via the mTOR/OGT pathway.Scientific Reports.2024, 14(1): 24369. 3. Fascia-derived stem cells enhance fat graft retention by promoting vascularization through the HMOX1-HIF-1α pathway

References

– 1. Seeley, TW, et al. U.S. Pat. Appl. Publ. 2007, US 20070292433 A1 20071220.

CAS Number

– 808118-40-3

Molecular Weight

– C19H16N2O5

Compound Purity

– 0.9974

SMILES

– Cc1nc(C(=O)NCC(O)=O)c(O)c2ccc(Oc3ccccc3)cc12

Pathway

– Apoptosis|||Chromatin/Epigenetic|||Metabolism|||Angiogenesis

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.