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Rotenone

SKU T2970-1 mL * 10 mM (in DMSO) Category Natural Product Brand: TargetMol

Price range: 67 CAD through 142 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

1 g 1 mL * 10 mM (in DMSO)5 g 500 mg

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Products Details

Product Description

– Rotenone (Rotocide) is a natural product and a botanical insecticide. Rotenone is a mitochondrial electron transport complex I inhibitor that promotes the production of reactive oxygen species in mitochondria and induces apoptosis.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T2970

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C23H22O6

Citations

– 1. Li Y, Sun H, Tian Z, et al. The determination of Plutella xylostella (L.) GSTs (PxGSTs) involved in the detoxification metabolism of Tolfenpyrad. Pest Management Science. 2020 2. Yi Y, Gao K, Lin P, et al. Staphylococcus aureus-Induced Necroptosis Promotes Mitochondrial Damage in Goat Endometrial Epithelial Cells. Animals. 2022, 12(17): 2218. 3. Zhang R, Fang J, Qi T, et al.Maternal aging increases offspring adult body size via transmission of donut-shaped mitochondria.Cell Research.2023: 1-14. 4. Ma W, Sun Y, Yan R, et al.OXCT1 functions as a succinyltransferase, contributing to hepatocellular carcinoma via succinylating LACTB.Molecular Cell.2023 5. Wang J, Chen J, Fan K, et al.Inhibition of Endoplasmic Reticulum Stress Cooperates with SLC7A11 to Promote Disulfidptosis and Suppress Tumor Growth upon Glucose Limitation.Advanced Science.2024: 2408789. 6. Ning X, Chen X, Li R, et al.Identification of a Novel Cuproptosis Inducer That Induces ER Stress and Oxidative Stress to Trigger Immunogenic Cell Death in Tumors.Free Radical Biology and Medicine.2025 7. Non-canonical hepatic androgen receptor mediates glucagon sensitivity in female mice through the PGC1α/ERRα/mitochondria axis

References

– Li N, et al. Mitochondrial complex I inhibitor rotenone induces apoptosis through enhancing mitochondrial reactive oxygen species production. J Biol Chem. 2003 Mar 7;278(10):8516-25.

CAS Number

– 83-79-4

Molecular Weight

– C23H22O6

Compound Purity

– 0.9988

SMILES

– O=C1C=2C(=C3C(O[C@@H](C(C)=C)C3)=CC2)O[C@]4([C@@]1(C=5C(OC4)=CC(OC)=C(OC)C5)[H])[H]

Pathway

– Autophagy|||Apoptosis|||Metabolism

Product type

– Natural Product

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.