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Ro 31-8220 Mesylate

SKU T6643-1 mL * 10 mM (in DMSO) Category Small Compound Brand: TargetMol

Price range: 70 CAD through 843 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

2 mg 1 mg 1 mL * 10 mM (in DMSO)10 mg 100 mg 25 mg 5 mg 50 mg

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Products Details

Product Description

– Ro 31-8220 Mesylate (Bisindolylmaleimide IX mesylate) is a pan-PKC inhibitor for PKC-α/βI/βII/γ/ε (IC50: 5/24/14/27/24 nM), and also shows potent inhibition against MSK1, MAPKAP-K1b, S6K1, and GSK3β.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T6643

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C25H23N5O2S·CH4O3S

Citations

– 1. Chen X, Xi Z, Liang H, et al. Melatonin prevents mice cortical astrocytes from hemin-induced toxicity through activating Nrf2/HO-1 signaling in vitro. Frontiers in Neuroscience. 2019, 13: 760

References

– Wilkinson SE, et al. Biochem J. 1993, 294 ( Pt 2), 335-337.

CAS Number

– 138489-18-6

Molecular Weight

– C25H23N5O2S·CH4O3S

Compound Purity

– 0.9918

SMILES

– CS(O)(=O)=O.Cn1cc(C2=C(C(=O)NC2=O)c2cn(CCCSC(N)=N)c3ccccc23)c2ccccc12

Pathway

– Chromatin/Epigenetic|||Cytoskeletal Signaling

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.