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Rhynchophylline

SKU T6S0659-1 mL * 10 mM (in DMSO) Category Natural Product Brand: TargetMol

Price range: 77 CAD through 309 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

1 mL * 10 mM (in DMSO)10 mg 25 mg 5 mg 50 mg

Clear

Products Details

Product Description

– 1. Rhynchophylline (Mitrinermine) can protect against ischemic damage, probably via regulating the Akt/mTOR pathway. 2. Rhynchophylline can protect against glutamate-induced neuronal death, can inhibit MA impairment in cultured neurons in vitro. 3. Rhynchophylline and isorhynchophylline have a non-competitive antagonistic effect on the NMDA-type ionotropic glutamate receptors, suggest that these alkaloids exert their protective action against ischemia-induced neuronal damage by preventing NMDA, muscarinic M1, and 5-HT2 receptors-mediated neurotoxicity during ischemia.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T6S0659

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C22H28N2O4

References

– He Y , Zeng S Y , Zhou S W , et al. Effects of rhynchophylline on GluN1 and GluN2B expressions in primary cultured hippocampal neurons[J]. Fitoterapia, 2014, 98:166-173.

CAS Number

– 76-66-4

Molecular Weight

– C22H28N2O4

Compound Purity

– 0.9944

SMILES

– CCC1CN2CCC3(C2CC1C(=COC)C(=O)OC)C(=O)Nc1ccccc31

Pathway

– Membrane transporter/Ion channel|||NF-κB|||Metabolism

Product type

– Natural Product

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.