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(Rac)-SIS3 free base

SKU T12923-25 mg Category Small Compound Brand: TargetMol

Price range: 1,174 CAD through 2,448 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

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Products Details

Product Description

– SIS3 free base is a potent and selective inhibitor of Smad3 phosphorylation, effectively inhibiting the TGF-β1-induced myofibroblast differentiation of fibroblasts.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T12923

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C28H27N3O3

References

– Jinnin M, et al. Characterization of SIS3, a novel specific inhibitor of Smad3, and its effect on transforming growth factor-beta1-induced extracellular matrix expression. Mol Pharmacol. 2006 Feb;69(2):597-607. Epub 2005 Nov 15.

CAS Number

– 1009104-85-1

Molecular Weight

– C28H27N3O3

SMILES

– COc1cc2CCN(Cc2cc1OC)C(=O)C=Cc1c(-c2ccccc2)n(C)c2ncccc12

Target

– Others

Pathway

– Stem Cells

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.