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(R)-Posenacaftor (sodium)

$380$3,060

Products Details

Product Description

– (R)-Posenacaftor (R)-PTI-801) sodium is the R enantiomer of Posenacaftor. Posenacaftor is a cystic fibrosis transmembrane regulator (CFTR) protein modulator that corrects the folding and trafficking of CFTR protein. Posenacaftor is used for the research of cystic fibrosis (CF)[1].

Web ID

– HY-109187B

Storage Temperature

– 4°C (Powder, sealed storage, away from moisture)

Shipping

– Room Temperature

Applications

– COVID-19-immunoregulation

Molecular Formula

– C27H26NNaO5

References

Р[1]Benjamin Kopp, et al. Compositions et proc̩d̩s pour am̩liorer la fonction cftr dans des cellules affect̩es par la fibrose kystique. Patent WO2019156946.

CAS Number

– 2095064-09-6

Molecular Weight

– 467.49

Compound Purity

– 98.96

SMILES

– O=C(C1=CC(C2=C(C)C3=CC=CC=C3O2)=NC4=C(C)C=CC(O[C@@H](C)C5CCOCC5)=C14)O[Na]

Clinical Information

– No Development Reported

Research Area

– Inflammation/Immunology

Solubility

– DMSO : 38.33 mg/mL (ultrasonic)

Target

– CFTR

Pathway

– Membrane Transporter/Ion Channel

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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