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(R)-Nicardipine
$180 – $1,200
Products Details
Product Description
– (R)-Nicardipine ((R)-YC-93 free base) is the less active R enantiomer of Nicardipine. Nicardipine (YC-93) is a calcium channel blocker with an IC50 of 1 μM for blocking cardiac calcium channels. Nicardipine acts as an agent for chronic stable angina and for controlling blood pressure[1].
Web ID
– HY-12515C
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C26H29N3O6
References
– [1]Charnet P, et al. Electrophysiological analysis of the action of nifedipine and nicardipine on myocardial fibers. Fundam Clin Pharmacol. 1987;1(6):413-31.
CAS Number
– 76093-35-1
Molecular Weight
– 479.52
Compound Purity
– 99.64
SMILES
– O=C(C1=C(C)NC(C)=C(C(OCCN(C)CC2=CC=CC=C2)=O)[C@@H]1C3=CC=CC([N+]([O-])=O)=C3)OC
Clinical Information
– No Development Reported
Research Area
– Neurological Disease; Cardiovascular Disease
Solubility
– DMSO : 200 mg/mL (ultrasonic;warming;heat to 60°C)
Target
– Calcium Channel
Pathway
– Membrane Transporter/Ion Channel;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
