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QX77

SKU T4663-2 mg Category Small Compound Brand: TargetMol

Price range: 48 CAD through 920 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

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Products Details

Product Description

– QX77 is a chaperone-mediated autophagy (CMA) activator.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T4663

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C16H13ClN2O2

Citations

– 1. Liu C, Sun W, Zhu T, et al. Glia maturation factor-β induces ferroptosis by impairing chaperone-mediated autophagic degradation of ACSL4 in early diabetic retinopathy. Redox Biology. 2022: 102292.

References

– Zhang J, et al. Cystinosin, the small GTPase Rab11, and the Rab7 effector RILP regulate intracellular trafficking of the chaperone-mediated autophagy receptor LAMP2A. J Biol Chem. 2017 Jun 23;292(25):10328-10346

CAS Number

– 1798331-92-6

Molecular Weight

– C16H13ClN2O2

Compound Purity

– 0.9838

SMILES

– CC(=O)Nc1ccc(cc1)C1=Nc2ccc(Cl)cc2OC1

Pathway

– Autophagy

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.