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Pyridostatin Trihydrochloride

SKU T4457-1 mg Category Small Compound Brand: TargetMol

Price range: 56 CAD through 821 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

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Products Details

Product Description

– Pyridostatin Trihydrochloride (RR-82 Trihydrochloride) is a G-quadruplexe stabilizer, with a Kd of 490 nM.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T4457

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C31H35Cl3N8O5

Citations

– 1. Li C, Yin Z, Xiao R, et al.G-quadruplexes sense natural porphyrin metabolites for regulation of gene transcription and chromatin landscapes.Genome Biology.2022, 23(1): 1-29. 2. Wang J, Huang H, Zhao K, et al.G-quadruplex in Hepatitis B Virus pregenomic RNA Promotes its Translation.Journal of Biological Chemistry.2023: 105151. 3. Zhang Y, Cheng Y, Luo Q, et al.Distinguishing G-Quadruplexes Stabilizer and Chaperone for c-MYC Promoter G-Quadruplexes through Single-Molecule Manipulation.Journal of the American Chemical Society.2024

References

– Koirala D,etal.A single-molecule platform for investigation of interactions between G-quadruplexes and small-molecule ligands.Nat Chem. 2011 Aug 28;3(10):782-7.

CAS Number

– 2517456-88-9

Molecular Weight

– C31H35Cl3N8O5

Compound Purity

– 0.9969

SMILES

– Cl.Cl.Cl.NCCOc1cc(nc(c1)C(=O)Nc1cc(OCCN)c2ccccc2n1)C(=O)Nc1cc(OCCN)c2ccccc2n1

Pathway

– DNA Damage/DNA Repair|||Cell Cycle/Checkpoint

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.