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PYR-41
Price range: 53 CAD through 1,728 CAD
For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.
Products Details
Product Description
– PYR-41 is the first cell-permeable inhibitor of ubiquitin-activating enzyme E1, with no activity at E2.
For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.
Web ID
– T6629
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C17H13N3O7
Citations
– 1. Kosmider O, Possémé C, Templé M, et al.VEXAS syndrome is characterized by inflammasome activation and monocyte dysregulation.Nature Communications.2024, 15(1): 910.
2. Qiu Q, He Z, Liu J, et al.Homeobox protein MSX-1 restricts hepatitis B virus by promoting ubiquitin-independent proteasomal degradation of HBx protein.PLoS pathogens.2025, 21(1): e1012897.
References
– Yang Y, et al. Cancer Res, 2007, 67(19), 9472-9481.
CAS Number
– 418805-02-4
Molecular Weight
– C17H13N3O7
Compound Purity
– 0.9825
SMILES
– CCOC(=O)c1ccc(cc1)N1NC(=O)C(=Cc2ccc(o2)[N+]([O-])=O)C1=O
Pathway
– Ubiquitination|||Apoptosis
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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