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Progesterone

SKU T0478-1 mL * 10 mM (in DMSO) Category Natural Product Brand: TargetMol

Price range: 61 CAD through 86 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

1 mL * 10 mM (in DMSO)100 mg 50 mg

Clear

Products Details

Product Description

– Progesterone (Pregn-4-ene-3,20-dione) is the major progestational steroid that is secreted primarily by the CORPUS LUTEUM and the PLACENTA. Progesterone acts on the UTERUS, the MAMMARY GLANDS and the BRAIN. It is required in EMBRYO IMPLANTATION; PREGNANCY maintenance, and the development of mammary tissue for MILK production.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T0478

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C21H30O2

Citations

– 1. Sun C C, Zhao S, Chu L L, et al. Di (2-ethyl-hexyl) Phthalate Disrupts Placental Growth in a Dual Blocking Mode. Journal of Hazardous Materials. 2021: 126815 2. Zeng X, Zhu S, Lu W, et al. Target identification among known drugs by deep learning from heterogeneous networks. Chemical Science. 2020, 11(7): 1775-1797. 3. Lin H, Lan K C, Ou Y C, et al. Highly Expressed Progesterone Receptor B Isoform Increases Platinum Sensitivity and Survival of Ovarian High-Grade Serous Carcinoma. Cancers. 2021, 13(21): 5578. 4. Wang D, Jin M, Zhou Y, et al. Loss of miR-29a Impairs Decidualisation of Endometrial Stromal Cells by Enhancing TET3 Binding to the Col1A1 Promoter. iScience. 2021 24 September 5. Zhang S, Sun C, Zhao S, et al. Exposure to DEHP or its metabolite MEHP promotes progesterone secretion and inhibits proliferation in mouse placenta or JEG-3 cells. Environmental Pollution. 2020, 257: 113593 6. Cui L, Xu F, Xu C, et al.Circadian gene Rev-erbα influenced by sleep conduces to pregnancy by promoting endometrial decidualization via IL-6-PR-C/EBPβ axis.Journal of Biomedical Science.2022, 29(1): 1-14. 7. Zhao W, Xu C, Peng L, et al.cAMP/PKA signaling promotes AKT deactivation by reducing CIP2A expression, thereby facilitating decidualization.Molecular and Cellular Endocrinology.2023: 111946.

References

– Owen GI, et al. J Biol Chem,1998, 273(17), 10696-10701.

CAS Number

– 57-83-0

Molecular Weight

– C21H30O2

Compound Purity

– 0.9989

SMILES

– [H][C@@]12CC[C@H](C(C)=O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CCC2=CC(=O)CC[C@]12C

Target

– PARP

Pathway

– Neuroscience|||Metabolism|||Others|||Endocrinology/Hormones|||GPCR/G Protein

Product type

– Natural Product

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.