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Products Details
Product Description
– Endogenous peptide agonist of Mas related GPR X2 (MRGPRX2, EC50 = 251 nM). Also a noncompetitive nicotinic cholinergic antagonist. Inhibits nicotine-stimulated catecholamine secretion from PC12 cells in vitro, and from sympathetic nerve endings and adrenal chromaffin cells in vivo. Corresponds to amino acids 1 – 20 of proadrenomedullin. Antihypertensive.
For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.
Web ID
– TP1490
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C112H178N36O27
References
– Mahata M, et al. Proadrenomedullin N-terminal 20 peptide: minimal active region to regulate nicotinic receptors. Hypertension. 1998 Nov;32(5):907-16.
CAS Number
– 150238-87-2
Molecular Weight
– C112H178N36O27
SMILES
– C([C@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC1=CC=CC=C1)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CCCNC(=N)N)NC([C@H](C)N)=O)=O)CC(C)C)=O)CC(O)=O)=O)[C@H](C)C)=O)C)=O)CO)=O)CCC(O)=O)=O)=O)CCCNC(=N)N)=O)CCCCN)=O)CCCCN)=O)C(N[C@H](C(N[C@H](C(N[C@@H](CC=2C=3C(NC2)=CC=CC3)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CCCNC(=N)N)C(N)=O)=O)CO)=O)CC(C)C)=O)C)=O)=O)CCCCN)=O)CC(N)=O)=O)C=4C=5C(NC4)=CC=CC5
Product type
– Peptide
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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