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PQR530
Price range: 46 CAD through 685 CAD
Products Details
Product Description
– PQR530 is a highly potent dual pan-PI3K/mTORC1/2 inhibitor. PQR530 inhibited protein kinase B (PKB, pSer473) and ribosomal protein S6 (pS6, pSer235/236) phosphorylation with IC50 values of 0.07 μM. It also showing antitumor activity.
Web ID
– T16567
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C18H23F2N7O2
References
– Denise Rageot, et al. Abstract 140: Discovery and biological evaluation of PQR530, a highly potent dual pan-PI3K/mTORC1/2 inhibitor. Cancer Res 2017;77(13 Suppl).
CAS Number
– 1927857-61-1
Molecular Weight
– C18H23F2N7O2
Compound Purity
– 0.9978
SMILES
– C[C@H]1COCCN1c1nc(nc(n1)-c1cnc(N)cc1C(F)F)N1CCOCC1
Target
– Others
Pathway
– PI3K/Akt/mTOR signaling
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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