Download Files:
Pomalidomide-PEG1-C2-N3
72 CAD
Only 1000 item(s) left in stock.
For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.
Products Details
Product Description
– Pomalidomide-PEG1-C2-N3, a conjugate of an E3 ligase ligand-linker, incorporates the cereblon ligand based on Pomalidomide and a 1-unit PEG linker, commonly used in PROTAC technology. This compound enables the design of the selective CDK6 PROTAC degrader CP-10, which effectively induces CDK6 degradation with a DC50 value of 2.1 nM[1].
For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.
Web ID
– T17904
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C17H18N6O5
References
– Su S, et al. Potent and Preferential Degradation of CDK6 via Proteolysis Targeting Chimera Degraders. J Med Chem. 2019 Aug 2.
CAS Number
– 2271036-44-1
Molecular Weight
– C17H18N6O5
SMILES
– [N-]=[N+]=NCCOCCNC1=CC=CC=2C(=O)N(C(=O)C12)C3C(=O)NC(=O)CC3
Target
– Gamma-secretase|||Beta Amyloid
Pathway
– Others
Product type
– PROTAC
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
Related Products
1000 in stock
Proudly representing
150+ years of combined research-supply heritage
