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PNU-282987

SKU T2422-1 mL * 10 mM (in DMSO) Category Small Compound Brand: TargetMol

Price range: 66 CAD through 936 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

1 mL * 10 mM (in DMSO)10 mg 100 mg 200 mg 25 mg 5 mg 50 mg

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Products Details

Product Description

– PNU-282987 is a selective α7 nicotinic acetylcholine receptor(α7 nAChR) agonist with Ki of 26 nM; no affinity for α1β1γδ and α3β4 nAChRs (IC50 ≥ 60 μM).

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T2422

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C14H18Cl2N2O

Citations

– 1. Zhang T, Yang K, Chen Y, et al. Impaired autophagy flux by lncRNA NEAT1 is critical for inflammation factors production in human periodontal ligament stem cells with nicotine treatment. Journal of Periodontal Research. 2022 2. Geng Y X, Lv H, Liu Y, et al.Electroacupuncture at Zusanli (ST36) Alleviate Intestinal Ischemia‐Reperfusion Injury by Regulating the Cholinergic‐miRNA 124 Pathway.Neurogastroenterology & Motility.2024: e14971.

References

– Bodnar AL, et al. J Med Chem. 2005 Feb 24;48(4):905-8.

CAS Number

– 123464-89-1

Molecular Weight

– C14H18Cl2N2O

Compound Purity

– 0.9992

SMILES

– Cl.C1CN2CCC1[C@H](C2)NC(=O)c1ccc(cc1)Cl

Pathway

– Neuroscience

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.