PKC-iota inhibitor 1

SKU T8764-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 184 CAD through 4,032 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Products Details

Product Description

– PKC-iota inhibitor 1 is an inhibitor of protein kinase C-iota (PKC-ι; IC50: 0.34 μM)
For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T8764

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C21H22N6O

Citations

– 1. Jiao J, Ruan L, Cheng C, et al.Paired protein kinases PRKCI-RIPK2 promote pancreatic cancer growth and metastasis via enhancing NF-κB/JNK/ERK phosphorylation.Molecular Medicine.2023, 29(1): 1-17.

References

– Kwiatkowski J, et al. Fragment-based Discovery of a Small-Molecule Protein Kinase C-iota Inhibitor Binding Post-kinase Domain Residues. ACS Med Chem Lett. 2019 Feb 15;10(3):318-323.

CAS Number

– 2328094-11-5

Molecular Weight

– C21H22N6O

Compound Purity

– 0.9882

SMILES

– Nc1ncc(cc1C(=O)Nc1ccncc1)-c1cccc(c1)N1CCNCC1

Pathway

– Chromatin/Epigenetic|||Cytoskeletal Signaling

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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For Research Use Only. All Immunomart products are sold strictly for laboratory research use only (RUO). Not for human or veterinary consumption, therapeutic, or diagnostic use.