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(-)-Pinoresinol

Products Details

Product Description

– (-)-Pinoresinol is a plant-derived tetrahydrofuran lignan that inhibits α-glucosidase and acts as a hypoglycemic agent. (-)-Pinoresinol has some anti-inflammatory effects and acts as a chemopreventive agent, inducing increased apoptosis and cell cycle G2/M arrest[1].

Web ID

– HY-126067

Shipping

– Room temperature

Applications

– COVID-19-immunoregulation

Molecular Formula

– C20H22O6

References

– [1]Lucia Fini, et al. Chemopreventive properties of pinoresinol-rich olive oil involve a selective activation of the ATM-p53 cascade in colon cancer cell lines. Carcinogenesis. 2008 Jan;29(1):139-46.|[2]Alexandrine During, et al. Among plant lignans, pinoresinol has the strongest antiinflammatory properties in human intestinal Caco-2 cells. J Nutr. 2012 Oct;142(10):1798-805.

CAS Number

– 81446-29-9

Molecular Weight

– 358.39

SMILES

– OC1=CC=C([C@@H]2OC[C@]3([H])[C@@]2([H])CO[C@H]3C4=CC=C(O)C(OC)=C4)C=C1OC

Clinical Information

– No Development Reported

Research Area

– Inflammation/Immunology

Solubility

– 10 mM in DMSO

Target

– Apoptosis;Glucosidase

Pathway

– Apoptosis;Metabolic Enzyme/Protease

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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