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Products Details
Product Description
– PIM1-IN-4 (Compound 8) is a potent inhibitor of PIM1. PIM1-IN-4 reveals strong inhibition of five other enzymes, i.e., SGK-1, PKA, CaMK-1, GSK3β, and MSK1. PIM1-IN-4 has the potential for the research of cancer diseases[1].
Web ID
– HY-143898
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C27H25BrCl2CuN6O
References
– [1]Wittmann C, et al. Highly Antiproliferative Latonduine and Indolo[2,3-c]quinoline Derivatives: Complex Formation with Copper(II) Markedly Changes the Kinase Inhibitory Profile. J Med Chem. 2022 Feb 10;65(3):2238-2261.
CAS Number
– 2762767-48-4
Molecular Weight
– 663.88
SMILES
– BrC1=CC=C(C2=C1)NC3=C2C4=C([N]5=C3N[N]6=C(C7=CC=C(C=[N]7[Cu]65(Cl)Cl)CN8CCOCC8)C)C=CC=C4
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Pim
Isoform
– PIM1
Pathway
– JAK/STAT Signaling
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
