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Picrotoxinin

SKU T16535-5 mg Category Natural Product Brand: TargetMol

Price range: 48 CAD through 190 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

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Products Details

Product Description

– Picrotoxinin is a blocker of chloride channel and a noncompetitive antagonist of GABAA with an IC50 of 1.15 μM for α1β2γ2L GABAA. Picrotoxinin shows convulsant properties.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T16535

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C15H16O6

Citations

– 1. Wang L, Wang K, Chen Y, et al.NLRP3 Inflammasome Inhibition After Pilocarpine-Induced Status Epilepticus Attenuates Chronic Inflammation in Epileptic Mice.Journal of Inflammation Research.2024: 6143-6158.

References

– Ng CC, et al. Effects of bilobalide, ginkgolide B and picrotoxinin on GABA

CAS Number

– 17617-45-7

Molecular Weight

– C15H16O6

Compound Purity

– 0.9807

SMILES

– [H][C@@]12C[C@@]3(O)[C@]4([H])[C@H](C(C)=C)[C@@]([H])(OC4=O)[C@@]4([H])OC(=O)[C@]1(O2)[C@@]34C

Target

– Endogenous Metabolite

Pathway

– Neuroscience|||Membrane transporter/Ion channel

Product type

– Natural Product

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.