physalin F

SKU T8716-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 72 CAD through 776 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Products Details

Product Description

– Physalin F is a natural blocker of CaV2.3 (R-type) and CaV2.2 (N-type) voltage-gated calcium channels.It is a secosteroid with potent anti-inflammatory and immunomodulatory activities. Physalin F induces apoptosis of PBMC, decreasing the spontaneous proliferation and cytokine production caused by Human T-lymphotropic virus type 1 (HTLV-1) infection
For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T8716

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C28H30O10

References

– Pinto L A , Meira, Cássio S, Villarreal C F , et al. Physalin F, a seco-steroid from Physalis angulata L. has immunosuppressive activity in peripheral blood mononuclear cells from patients with HTLV1-associated myelopathy[J]. Biomedicine & Pharmacotherapy, 2016, 79:129-134.

CAS Number

– 57423-71-9

Molecular Weight

– C28H30O10

Compound Purity

– 0.9907

SMILES

– [H][C@@]12C(=O)[C@]34O[C@@]11[C@](O)(CC[C@@]5([H])[C@@]3([H])C[C@H]3O[C@]33CC=CC(=O)[C@]53C)C(=O)O[C@@]1(C)[C@@]1([H])C[C@]2(C)[C@@]([H])(CO4)C(=O)O1

Pathway

– Apoptosis|||Membrane transporter/Ion channel|||Metabolism

Product type

– Natural Product

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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For Research Use Only. All Immunomart products are sold strictly for laboratory research use only (RUO). Not for human or veterinary consumption, therapeutic, or diagnostic use.