PGD97

SKU TP3018-10 mg Category Brand:

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

This product is currently out of stock and unavailable.

Products Details

Product Description

– PGD97 is a selective cyclic peptide inhibitor targeting the CAL/CFTR interaction, with its desulfurization-cyclized form exhibiting a KD value of 6 nM for the CAL PDZ domain. It shows a selectivity of at least 130-fold over the NHERF1/2 PDZ domains. PGD97 stabilizes F508del-CFTR on the cell membrane, enhancing CFTR function necessary for normal pulmonary fluid balance. This compound is applicable in cystic fibrosis research.
For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– TP3018

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C74H111N23O14S3

CAS Number

– 2717490-36-1

Molecular Weight

– C74H111N23O14S3

SMILES

– C(C=1C=2C(SC1)=CC=CC2)[C@H]3C(=O)N4[C@](C(=O)N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H]([C@@](C)(C)C)C(O)=O)=O)CCCNC(=N)N)=O)[C@@H](C)O)=O)C(C)(C)SSC[C@H](NC(C)=O)C(=O)N[C@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC5=CC6=C(C=C5)C=CC=C6)C(=O)N3)(CCCC4)[H]

Product type

– Peptide

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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For Research Use Only. All Immunomart products are sold strictly for laboratory research use only (RUO). Not for human or veterinary consumption, therapeutic, or diagnostic use.