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PF-03715455

SKU T16477-25 mg Category Small Compound Brand: TargetMol

Price range: 4,352 CAD through 7,840 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

100 mg 25 mg 50 mg

Clear

Products Details

Product Description

– PF-03715455 potently inhibits LPS-induced TNFα production in human whole blood (IC50=1.7 nM). PF-03715455 is an effective inhibitor of inhaled p38 MAPK. PF-03715455 displays some selectivity for p38α over p38β (respective IC50: 0.88 and 23 nM). PF-03715455 has the potential for the treatment of COPD.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T16477

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C35H34ClN7O3S2

References

– Norman P, et al. Investigational p38 inhibitors for the treatment of chronic obstructive pulmonary disease. Expert Opin Investig Drugs. 2015 Mar;24(3):383-92.

CAS Number

– 1056164-52-3

Molecular Weight

– C35H34ClN7O3S2

SMILES

– S(C1=CN2C(=NN=C2C=C1)C3=C(SCCO)C=CC=C3)C4=C(CNC(NC=5N(N=C(C(C)(C)C)C5)C6=CC(Cl)=C(O)C=C6)=O)C=CC=C4

Target

– Others

Pathway

– MAPK

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.