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PD0325901-O-C2-dioxolane

Name: PD0325901-O-C2-dioxolane | Research Reagent — Buy Online | Immunomart
Brand: TargetMol
SKU: T40217-1 mg
Price: 179 CAD
Availability: InStock

SKU T40217-1 mg Category PROTAC Brand: TargetMol

179 CAD

Only 1000 item(s) left in stock.

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Products Details

Product Description

– The main body of PD0325901-O-C2-dioxolane is PD0325901, which is a typical non-ATP-competitive MEK1/2 (mitogen-activated protein kinase) inhibitor occupying a variant-binding pocket near the ATP-binding site, with anticancer effects of decreasing ERK phosphorylation and inhibiting cell proliferation.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T40217

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C18H16F3IN2O4

References

– Wei J, et al. Discovery of a First-in-Class Mitogen-Activated Protein Kinase Kinase 1/2 Degrader. J Med Chem. 2019;62(23):10897-10911.

CAS Number

– 2581116-22-3

Molecular Weight

– C18H16F3IN2O4

SMILES

– O=C(NOCCC1OCCO1)C2=CC=C(F)C(F)=C2NC3=CC=C(I)C=C3F

Pathway

– MAPK|||PROTAC

Product type

– PROTAC

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.