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PBRM1-BD2-IN-2

SKU T60156-1 mL * 10 mM (in DMSO) Category Small Compound Brand: TargetMol

Price range: 187 CAD through 3,632 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

1 mg 1 mL * 10 mM (in DMSO)10 mg 100 mg 25 mg 5 mg 50 mg 500 mg

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Products Details

Product Description

– PBRM1-BD2-IN-2, a selective and cell-active inhibitor of the polybromo-1 (PBRM1) bromodomain, exhibits binding affinity and inhibitory activity specifically targeting the PBRM1-BD2 domain, with Kd and IC50 values of 9.3 μM and 1.0 μM, respectively. This compound is utilized in cancer research.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T60156

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C14H9Cl2FN2O

References

– Shifali Shishodia, et al. Selective and Cell-Active PBRM1 Bromodomain Inhibitors Discovered through NMR Fragment Screening. J Med Chem. 2022 Oct 13.

CAS Number

– 2819989-57-4

Molecular Weight

– C14H9Cl2FN2O

Compound Purity

– 1

SMILES

– O=C1C=2C(NC(N1)C3=C(Cl)C=CC=C3F)=CC=CC2Cl

Pathway

– Chromatin/Epigenetic

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.