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Olorofim

SKU T27300-1 mg Category Small Compound Brand: TargetMol

Price range: 624 CAD through 4,480 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

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Products Details

Product Description

– Olorofim(F-901318)is a novel selective antifungal compound targeting pyrimidine biosynthesis in mycobacteria, with inhibitory effect on Aspergillus fumigatus DHODH (IC50: 44 nM), but little inhibitory effect on human DHODH (>100 uM).Olorofim has good efficacy against a variety of pathogenic filamentous and dimorphic fungi, such as Penicillium spp, P. dermatitidis spp and Fusarium spp.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T27300

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C28H27FN6O2

Citations

– 1. Shao Y, Shao J, de Hoog S, et al.Emerging Antifungal Resistance in Trichophyton mentagrophytes: Insights from Susceptibility Profiling and Genetic Mutation Analysis.Emerging Microbes & Infections.2025 (just-accepted): 2450026.

References

– Mirbzadeh Ardakani E, et al. Olorofim Effectively Eradicates Dermatophytes In Vitro and In Vivo. Antimicrob Agents Chemother. 2021;65(12):e0138621.

CAS Number

– 1928707-56-5

Molecular Weight

– C28H27FN6O2

Compound Purity

– 0.9928

SMILES

– C(C(NC1=CC=C(C=C1)N2CCN(CC2)C=3N=CC(F)=CN3)=O)(=O)C4=C(C=C(C)N4C)C5=CC=CC=C5

Pathway

– Metabolism|||Microbiology/Virology

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.