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NV03

SKU T12271-25 mg Category PROTAC Brand: TargetMol

Price range: 2,640 CAD through 5,568 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

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Products Details

Product Description

– NV03 is a potent and selective antagonist of the UHRF1 (Ubiquitin-like with PHD and RING finger domains 1)-H3K9me3 interaction, binding to the UHRF1 tandem tudor domain with a Kd of 2.4 μM. NV03 holds potential as an anticancer therapeutic [1].

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T12271

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C19H27N5O2S

References

– Senisterra G, et al. Discovery of Small-Molecule Antagonists of the H3K9me3 Binding to UHRF1 Tandem Tudor Domain. SLAS Discov. 2018 Oct;23(9):930-940.

CAS Number

– 2448341-58-8

Molecular Weight

– C19H27N5O2S

SMILES

– CCN(CC)CCCNC(=O)Cn1nc(C)n2c3ccsc3c(C)c2c1=O

Target

– NOD-like Receptor (NLR)|||RIP kinase

Pathway

– Others

Product type

– PROTAC

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.