Notch 3 Protein, Human, Recombinant (His)

SKU TMPK-01396-100 μg Category Recombinant-Protein Brand: TargetMol

Price range: 779 CAD through 3,120 CAD

Size

100 μg 500 μg

Clear

Products Details

Product Description

– Human Notch-3 is part of the Notch family of type I transmembrane glycoproteins involved in a number of early-event developmental processes. The extracellular domain of Notch receptors interact with the extracellular domain of transmembrane ligands Jagged, Delta, and Serrate expressed on the surface of a neighboring cell. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– TMPK-01396

Storage Temperature

– -20℃

Shipping

– Blue Ice

References

– Wu Y, et al. Therapeutic antibody targeting of individual Notch receptors[J]. NATURE, 2010, 464(7291):1052-1057.

Molecular Weight

Product type

– Recombinant-Protein

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.