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Norepinephrine

SKU T7044-1 mL * 10 mM (in DMSO) Category Natural Product Brand: TargetMol

Price range: 66 CAD through 80 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

1 mL * 10 mM (in DMSO)100 mg

Clear

Products Details

Product Description

– Norepinephrine (Levophed) can stimulate apoptosis in adult rat ventricular myocytes by activation of the β-adrenergic pathway. It can up-regulate the expression of vascular endothelial growth factor, matrix metalloproteinase (MMP)-2, and MMP-9 in nasopharyngeal carcinoma tumour cells.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T7044

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C8H11NO3

Citations

– 1. Wang H, Wu Y, Zou Q, et al. A biosensing system using a multiparameter nonlinear dynamic analysis of cardiomyocyte beating for drug-induced arrhythmia recognition. Microsystems & Nanoengineering. 2022, 8(1): 1-14 2. Chen H, Cao N, Wang L, et al. Biased activation of β2-AR/Gi/GRK2 signal pathway attenuated β1-AR sustained activation induced by β1-adrenergic receptor autoantibody. Cell death discovery,. 2021, 7(1): 1-11. 3. Gu Y, Zhang M, Liu X, et al Impact of bilateral sympathetic stellate ganglionectomy on TGF-β1 signaling pathway in rats with chronic volume overload. Frontiers in Physiology. 2020, 11: 375 4. Wang Y, Wang X, Wang K, et al.Chronic stress accelerates glioblastoma progression via DRD2/ERK/β-catenin axis and Dopamine/ERK/TH positive feedback loop.Journal of Experimental & Clinical Cancer Research.2023, 42(1): 1-17. 5. Chen X, Wang K, Chen J, et al.Integrative residue-intuitive machine learning and MD Approach to Unveil Allosteric Site and Mechanism for β2AR.Nature Communications.2024, 15(1): 8130. 6. Zhao X, Li F, Cheng C, et al.Social isolation promotes tumor immune evasion via β2-adrenergic receptor.Brain, Behavior, and Immunity.2024

References

– Jhaveri DJ, et al. Norepinephrine directly activates adult hippocampal precursors via beta3-adrenergic receptors. J Neurosci. 2010 Feb 17;30(7):2795-806.

CAS Number

– 51-41-2

Molecular Weight

– C8H11NO3

Compound Purity

– 0.9984

SMILES

– [C@@H](CN)(O)C1=CC(O)=C(O)C=C1

Pathway

– Autophagy|||Proteases/Proteasome|||GPCR/G Protein|||Metabolism|||Neuroscience

Product type

– Natural Product

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.