Nilotinib monohydrochloride monohydrate

SKU T2147-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 48 CAD through 187 CAD

Products Details

Product Description

– Nilotinib monohydrochloride monohydrate (Nilotinib (monohydrochloride monohydrate)) is significantly potent BCR-ABL against, is a second generation tyrosine kinase inhibitor (TKI), and is active against many BCR-ABL mutants.

Web ID

– T2147

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C28H22F3N7O.HCl.H2O

References

– Sako H , Fukuda K , Saikawa Y , et al. Antitumor Effect of the Tyrosine Kinase Inhibitor Nilotinib on Gastrointestinal Stromal Tumor (GIST) and Imatinib-Resistant GIST Cells[J]. PLOS ONE, 2014, 9(9):e107613.

CAS Number

– 923288-90-8

Molecular Weight

– C28H22F3N7O.HCl.H2O

Compound Purity

– 0.9993

SMILES

– O.Cl.Cc1cn(cn1)-c1cc(NC(=O)c2ccc(C)c(Nc3nccc(n3)-c3cccnc3)c2)cc(c1)C(F)(F)F

Pathway

– Tyrosine Kinase/Adaptors|||Autophagy|||Angiogenesis|||Cytoskeletal Signaling

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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