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Napabucasin

$77$1,815

Products Details

Product Description

– Napabucasin (BBI608) is a STAT3 inhibitor which blocks stem cell activity in cancer cells.

Web ID

– HY-13919

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Applications

– Cancer-Kinase/protease

Molecular Formula

– C14H8O4

References

– [1]Zhang Y, et al. Suppression of prostate cancer progression by cancer cell stemness inhibitor napabucasin. Cancer Med. 2016 Jun;5(6):1251-8.

CAS Number

– 83280-65-3

Molecular Weight

– 240.21

Compound Purity

– 98.85

SMILES

– O=C(C1=C2OC(C(C)=O)=C1)C3=C(C2=O)C=CC=C3

Clinical Information

– Phase 3

Research Area

– Cancer

Solubility

– DMSO : 4.44 mg/mL (ultrasonic)|H2O : ≥ mg/mL

Target

– STAT

Isoform

– STAT3

Pathway

– JAK/STAT Signaling;Stem Cell/Wnt

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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