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N-piperidine Ibrutinib hydrochloride

SKU T12152-1 mL * 10 mM (in DMSO) Category PROTAC Brand: TargetMol

Price range: 62 CAD through 1,211 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

1 mg 1 mL * 10 mM (in DMSO)10 mg 100 mg 25 mg 5 mg 50 mg

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Products Details

Product Description

– N-piperidine Ibrutinib hydrochloride is a potent BTK inhibitor, a BTK ligand, inhibits WT BTK and C481S BTK, which can be used to synthesize a range of PROTAC molecules.N-piperidine Ibrutinib hydrochloride has potential anticancer N-piperidine Ibrutinib hydrochloride has potential anticancer activity, inhibiting the growth and proliferation of cancer cells.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T12152

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C22H23ClN6O

References

– Buhimschi AD, et al. Targeting the C481S Ibrutinib-Resistance Mutation in Bruton’s Tyrosine Kinase Using PROTAC-Mediated Degradation. Biochemistry. 2018 Jul 3;57(26):3564-3575.

CAS Number

– 2231747-18-3

Molecular Weight

– C22H23ClN6O

Compound Purity

– 0.9883

SMILES

– Cl.Nc1ncnc2n(nc(-c3ccc(Oc4ccccc4)cc3)c12)C1CCNCC1

Target

– Antiviral|||Antifungal

Pathway

– Angiogenesis|||Tyrosine Kinase/Adaptors

Product type

– PROTAC

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.